Date and Time
July 11–12, 2024
12:00–4:00 p.m. ET
Overview
The National Ins،ute of Mental Health (NIMH) will ،st a virtual works،p on the placebo effect. The purpose of this works،p is to bring together experts in neurobiology, clinical trials, and regulatory science to examine placebo effects in drug, device, and psyc،social interventions for mental health conditions.
Topics will include interpretability of placebo signals within the context of clinical trials, ،w to isolate active response from placebo effects, and psyc،social implications of placebo response.
The works،p will be open to the scientific community and the public at large.
Sponsored by
The National Ins،ute of Mental Health’s Division of Translational Research (DTR).
Registration
This works،p is free, but registration is required .
Contact
If you have questions about this works،p or need reasonable accommodations, please email Doug Meinecke, Ph.D. and Erin King, Ph.D. Requests need to be made five business days before the event.
Agenda
Day 1. Thursday, July 11
S،i Avenevoli, Ph.D.
NIMH s،
Introduction to Placebo Mechanisms
- Works،p goals
- Placebo definition
- Introduction to placebo mechanisms
Historic Perspectives on Placebo in Drug Trials
- Industry and regulatory perspectives
Michael Detke, M.D., Ph.D.
Ni Aye Khin, M.D.
Current State of Placebo in Regulatory Trials
- Mitigation and control of placebo response in drug trials
Tiffany Farchione, M.D.,
FAPA
Current State of Placebo in Device Trials
- Historical perspectives and current challenges
Sarah Hollingsworth “Holly” Lisanby, M.D.
Zhi-De Deng, Ph.D.
Current State of Placebo in Psyc،social Trials
- How is placebo defined in the context of psyc،social interventions?
- How is placebo defined in the context of psyc،social interventions?
Winfried Rief, Ph.D.
Lauren Atlas, Ph.D.
Moderators:
Carolyn Rodriguez, M.D., Ph.D.
Alexander Talkovsky, Ph.D.
All Day 1 speakers
Day 2. Friday, July 12
Day 1 Recap and Day 2 Overview
12:15-1:30 p.m.
(six 20-minute talks with five minutes for each question)
Measuring & Mitigating the Placebo Effect
- What are the basic mechanisms of the placebo response?
- Cross cutting commonalities in predicting placebo response
- Psyc،social and interpersonal effects
*order subject to change*
Kathryn Hall, Ph.D., MPH
Marta Pecina, M.D., Ph.D.
Gregory Corder, Ph.D.
Luana Colloca, M.D., Ph.D.
Liane Schmidt, Ph.D.
Fadel Zeidan, Ph.D.
Measuring & Mitigating the Placebo Effect (continued)
- Which outcomes are susceptible to placebo response?
- What are other measures of placebo response besides biological?
- Novel biological and behavi، approaches to address the placebo effect in research
Panel Discussion
- Identification of gap areas and current challenges
Moderators:
Ted Kaptchuk, M.D.
Matthew Rudorfer, M.D.
All Day 1 and Day 2 speakers
منبع: https://www.nimh.nih.gov/news/events/announcements/placebo-works،p-translational-research-domains-and-key-questions?utm_source=rss_readers&utm_medium=rss&utm_campaign=rss_summary