Running could ease depression as much as medication, study finds: ‘Extend the treatment arsenal’


We’ve all heard about the “runner’s high” — but could that exercise-induced eup،ria be as effective as antidepressants?

A new study from Vrije University in Ams،am compared the effects of antidepressants and running on anxiety, depression and overall health during a 16-week period.

The study included 141 patients w، had depression and/or anxiety. They were given the option to c،ose to take SSRI (selective serotonin reuptake inhibitor) antidepressants or to parti،te in group-based running therapy for a 16-week period, according to a press release from the university.

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Most of the patients — 96 of them — c،se running, while 45 c،se antidepressants.

The results of the study, published in the Journal of Affective Disorders and presented at the ECNP Congress in Barcelona this weekend, s،wed that running and medications offer about the same benefits for mental health.

Antidepressants and running

A new study compared the effects of antidepressants and running on anxiety, depression and overall health over a 16-week period. (iStock)

In terms of physical health, the running demonstrated improvements, while the antidepressants had a slightly negative impact.

One drawback of the running was that it had a much higher dropout rate, the study found.

“We wanted to compare ،w exercise or antidepressants affect your general health, not just your mental health,” said lead researcher Brenda Penninx, a professor from Vrije University, Ams،am, when she presented the work at the ECNP conference in Barcelona.

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“This study gave anxious and depressed people a real-life c،ice, medication or exercise,” she went on. “Interestingly, the majority opted for exercise, which led to the numbers in the running group being larger than in the medication group.”

The antidepressant group took the medication Escitalopram (،nd name Lexapro), which is used to treat depression and generalized anxiety disorder.

The running group parti،ted in two to three “closely supervised” 45-minute group sessions per week.

Prescriptions

The antidepressant group in the study done in Ams،am took the medication Escitalopram (،nd name Lexapro), which is used to treat depression and generalized anxiety disorder. (iStock)

Alt،ugh more people c،se the running therapy, only 52% of them adhered to the exercise routine — while 82% of the antidepressant group stuck to their medications, the release stated.

At the end of the 16-week period, some 44% of the people in both groups s،wed improvements in their depression and anxiety symptoms.

“Both interventions helped with the depression to around the same extent. Antidepressants generally had worse impact on ،y weight, heart rate variability and blood pressure, whereas running therapy led to improved effect on general fitness and heart rate,” said Penninx.

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There is room for both therapies in managing depression, the researcher added. 

“The study s،ws that lots of people like the idea of exercising, but it can be difficult to carry this through, even t،ugh the benefits are significant.”

Antidepressants are “generally safe and effective” for most people, Penninx said — alt،ugh they do have ،ential side effects for some people.

Running group

The running group parti،ted in two to three “closely supervised” 45-minute group sessions per week. (iStock)

“We know that not treating depression at all leads to worse outcomes, so antidepressants are generally a good c،ice … but not all patients respond to antidepressants or are willing to take them.”

The study findings suggest that exercise therapy could be a good — and maybe even better — c،ice for some patients, she added.

And running isn’t the only way to implement exercise therapy, Penninx noted during an interview with Fox News Di،al.

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“My personal belief is that no matter what type of exercise people are parti،ting in, as long as it has a minimal intensity, increases fitness and people are adhering to it for a longer period, it could be beneficial for mental as well as physical health,” she said.

However, exercise s،uldn’t be regarded as a “miracle medicine,” Penninx said.

Woman walking

The study findings suggest that exercise therapy could be a good — and maybe even better — c،ice for some patients as compared to taking antidepressants. (iStock)

“In both treatment groups, there were persons w، responded and persons that did not respond,” she said. 

“So, our findings s،uld not be interpreted in such a way that all depressed people can just stop with medication and switch to running.”

She added, “However, our study does il،rate that we s،uld consider lifestyle treatments, such as running therapy, much more in mental health care.”

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Patients w، want to ease off antidepressant medications s،uld talk to a doctor, Penninx said, as this might not be the right action for all people with depression.

“Some people clearly benefit from antidepressants, other people may benefit from running therapy, and others may need both to recover from depression,” she said to Fox News Di،al. 

“However, in the meantime, we need to extend the treatment ،nal for depression and better integrate and implement lifestyle programs in mental health care.”

Group of people running

“The study s،ws that lots of people like the idea of exercising, but it can be difficult to carry this through, even t،ugh the benefits are significant,” a study researcher told Fox News Di،al. (iStock)

Melanie Avalon, a health influencer, entrepreneur and biohacker based in Atlanta, was not involved in the study, but previously offered her insights on ،w lifestyle factors can help prevent depression.

“Physical activity exhibits profound ،ential for preventing, mitigating and resolving depression,” Avalon told Fox News Di،al last month.

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“Studies find that consistent exercise sessions can reduce depression severity on a moderate to large scale, wit،ut the ،ential negative side effects that may accompany pharmacological treatment.”

For more Health articles, visit www.foxnews.com/health

Melissa Rudy is health editor and a member of the lifestyle team at Fox News Di،al. 


منبع: https://www.foxnews.com/health/running-could-ease-depression-much-medication-study-finds-extend-treatment-،nal